The Pakistani city of Karachi is in mourning after a powerful bomb ripped through a mainly Shia Muslim area, killing at least 45 people, the BBC.
Schools and businesses are closed after a strike was called to protest against the attack in Abbas Town.
No group has yet said it planted the bomb, which went off near a mosque as worshippers left evening prayers.
Pakistan’s Shia minority are the target of frequent sectarian attacks from Sunni militant groups.
Sunday night’s explosion destroyed several buildings and set others on fire, sending a huge column of smoke into the sky and causing a power cut in part of the city.
Police are investigating whether it was a suicide attack and some reports have spoken of a second explosion.
At least 150 people were wounded by the blast, police say.